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학력사항

  • 한국과학기술원 박사(생화학(효소학) 전공)
  • 한국과학기술원 석사(생화학(효소학) 전공)
  • 연세대학교 학사

논문

  • Characterization of two alkyl hydroperoxide reductase C homologs alkyl hydroperoxide reductase C_H1 and alkyl hydroperoxide reductase C_H2 in Bacillus subtilis, World Journal of Biological Chemistry, 2015.
  • Decreased serum level of thioredoxin 1 in female patients with pneumonia and its combinational use with haptoglobin for the specific diagnoses of pneumonia and lung canc, Pneumonia, 2015.
  • Thioredoxin 1 as a serum marker for ovarian cancer and its use in combination with CA125 for improving the sensitivity of ovarian cancer diagnoses, Biomarkers, 2014.
  • Thioredoxin 1 as a serum marker for breast cancer and its use in combination with CEA or CA15-3 for improving the sensitivity of breast cancer diagnoses, BMC Research Notes, 2014.
  • Interaction between Saccharomyces cerevisiae glutaredoxin 5 and SPT10 and their in vivo functions, Free Radical Biology & Medicine, 2012.
  • Preferential overexpression of glutaredoxin3 in human colon and lung carcinoma, Cancer Epidemiology, 2009.
  • Overexpression of Peroxiredoxin I and Thioredoxin1 in Human Breast Carcinoma, Journal of Expreimental and Clinical Cancer Research, 2009.
  • A glutaredoxin-fused thiol peroxidase acts as an important player in hydrogen peroxide detoxification in late-phased growth of Anabaena sp. PCC7120, Archives of Biochemistry and Biophysics, 2008.
  • Four thiol peroxidases contain a conserved GCT catalytic motif and act as a versatile array of lipid peroxidases in Anabaena sp. PCC7120, FREE RADICAL BIO MED, 2007.
  • 설피리독신과 알파-만노시다제 간의 단백질 결합 특성에 대한 고찰, 자연과학논문집, 2006.
  • Disulfide between Cys392 and Cys438 of human serum albumin is redox-active, which is responsible for the thioredoxin-supported lipid peroxidase activity, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2006.
  • Specific protein interaction of human Pag with Omi/HtrA2 and the activation of the protease activity of Omi/HtrA2, FREE RADICAL BIOLOGY AND MEDICINE, 2006.
  • Disulfide between Cys392 and Cys438 of human serum albumin is redox-active, which is responsible for the thioredoxin-supported lipid peroxidase activity, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2006.
  • Crystal Structure of the C107S/C112S Mutant of Yeast Nuclear 2-Cys Peroxiredoxin, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2005.
  • Crystallization and preliminary X-ray analysis of a truncated mutant of yeast nuclear thiol peroxidase, a novel atypical 2-Cys peroxiredoxin, Acta Crystallographica, 2005.
  • Characterization of a second gene encoding gamma-glutamyl transpeptidase from Shizosaccharomyces cerevisiae pombe, Canadian Journal of Microbilogy, 2005.
  • Yeast Two-hybrid System을 이용한 CTPx II 결합단백질 탐색 및 분석, 자연과학논문집, 2004.
  • 지렁이 (Lumbricus terrestis)로 부터 Thiol-Specific Antioxidant protein (TSA)의 분리 및 정제에 관한 연구, 자연과학논문집, 2004.
  • 고염 원시 박테리아 Halococcus agglomeratus)에 존재하는 TPx 분리 및 생화학적 특성 연구, 자연과학논문집, 2004.
  • Stress-dependent regulation of the gene encoding thioredoxin reductase from the fission yeast, FEMS Microbiology Letters, 2004.
  • Vibrio cholerae thiol peroxidase-glutathione fusion is a 2-cys TSA/AhpC subfamily acting as lipid hydroperoxiode reductase, J. Biol. Chem, 2004.
  • Escherichia coli periplasmic thiol peroxidase acts as lipid hydroperoxide peroxidase and the principal antioxidative function during anaerobic growth, J. Biol. Chem, 2004.
  • Haemophilus Influenzae TPx-Grx의 생화학적 특성연구, 자연과학논문집, 2004.
  • Characterization and regulation of gamma-glutamyl transpeptidase gene from the fission yeast Schizosaccharomyces pombe, Can. J. Microbiol., 2004.
  • Crystallization and preminary X-ray analysisi of E. coli p20, a novel thiol peroxidase, Acta Chystallographica Section D, Biological Crystallography, 2003.
  • Crystal Structure of Escherichia coli Thiol Peroxidase in the Oxidized State, J. Biol. Chem, 2003.
  • The Protein Interaction of saccharomyces cerevisiae cytopasmic thiol peroxidase II with SFH2p and its in vivo Function, J. Biol. Chem, 2003.
  • Nuclear Thiol Peroxidase (nTPx) act as alkylhydroperoxide, J. Biolo. Chem., 2003.
  • Msn2p/4p Act as a key transcriptional activator of yeast cTPx II, J. Biolo. Chem., 2002.
  • Thioredoxin-linked Lipid Hydroperoxide Peroxidase Activity of Human Serum Albumin in the Presence of Palmitoyl Coenzyme, Free Radical Biology and Medicine, 2001.
  • Interaction of Human Thiol-Specific Antioxidant Protein 1 with Erythrocyte Plasma Membrane, Biochemistry, 2000.
  • "25-kDa Thiol Peroxidase" (TPx Ⅱ) Acts as a "Housekeeping" Antioxidant., Journal of Biochemistry and Molecular Biology, 1999.
  • Ceruloplasmin Has a Distinct Active Site for the Catalyzing Glutathione-Dependent Reduction of Alkyl Hydroperoxide, Biochemistry, 1999.
  • Existencs of "25kDa Thiol Peroxidase" in Retina : Evidence for An Antioxidative Role, Journal of Microbiology and Biotechnology, 1998.
  • Purification and Characterization of a Bacillus sp. DG0303 Thermostable α-Glucosidase with Oligo-1,6-glucosidase Activity, J. Microbiol. Biotechnol., 1998.
  • 대장균 thiol peroxidase 단백질의 과량생산, 배재대학원 논문집, 1996.
  • 소 뇌로부터 Thiol-Specific Antioxidant 단백의 분리 및 그 특성에 관한 연구, 배재대학원 논문집, 1996.
  • Mutation and Mutagenesis of Thiol Peroxidase of Escherichia coli and a New Type of Thiol Peroxidase Family, Journal of Bacteriology, 1996.
  • Purification and Characterization of Thiol-Specific Antioxidant Protein from Human Liver : A Mer5-like Human Isoenzyme, J. Biochem. Mol. Biol., 1996.
  • Glutathione-Linked Thiol Peroxidase Activity of Human Serum Albumin : A Possible Antioxidant Role of Serum Albumin in Blood Plasma, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996.
  • THIOREDOXIN-LINKED PEROXIDASE FROM HUMAN RED BLOOD, Biochemical and biophysical reserch communications, 1995.
  • Thioredoxin-linked "Thiol Peroxidase" from Periplasmic Space of Escherichia coli, The Journal of Biological Chemistry, 1995.

저역서

  • 레닌저 생화학 (상) (하), 도서출판 월드사이언스, 2006.
  • Redox Regulation of Cell Signalling and Its Clinical Application, Marcel Dekker, Inc, 1999.
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